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1.
Safety, Tolerability and Pharmacokinetics of Half-Life Extended Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Monoclonal Antibodies AZD7442 (Tixagevimab-Cilgavimab) in Healthy Adults.
J Infect Dis
; 227(10): 1153-1163, 2023 05 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36683419
2.
Intravenous Amisulpride Does Not Meaningfully Prolong the QTc Interval at Doses Effective for the Management of Postoperative Nausea and Vomiting.
Anesth Analg
; 132(1): 150-159, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31913911
3.
Navafenterol (AZD8871) in healthy volunteers: safety, tolerability and pharmacokinetics of multiple ascending doses of this novel inhaled, long-acting, dual-pharmacology bronchodilator, in two phase I, randomised, single-blind, placebo-controlled studies.
Respir Res
; 21(Suppl 1): 212, 2020 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32907575
4.
Navafenterol (AZD8871) in patients with mild asthma: a randomised placebo-controlled phase I study evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of single ascending doses of this novel inhaled long-acting dual-pharmacology bronchodilator.
Respir Res
; 21(Suppl 1): 211, 2020 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32907576
5.
Pharmacokinetics, pharmacodynamics and safety of the inverse retinoic acid-related orphan receptor γ agonist AZD0284.
Br J Clin Pharmacol
; 86(7): 1398-1405, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32067249
6.
Clinical safety, tolerability, pharmacokinetics and effects on urinary electrolyte excretion of AZD9977, a novel, selective mineralocorticoid receptor modulator.
Br J Clin Pharmacol
; 84(7): 1486-1493, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29468715
7.
A Randomized Phase I Study of the Anti-Interleukin-33 Antibody Tozorakimab in Healthy Adults and Patients With Chronic Obstructive Pulmonary Disease.
Clin Pharmacol Ther
; 115(3): 565-575, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38115209
8.
Three-Year Safety, Tolerability, and Health-Related Quality of Life Outcomes of Adjuvant Osimertinib in Patients With Resected Stage IB to IIIA EGFR-Mutated NSCLC: Updated Analysis From the Phase 3 ADAURA Trial.
J Thorac Oncol
; 18(9): 1209-1221, 2023 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37236398
9.
Effect of Oral Semaglutide on the Pharmacokinetics of Levonorgestrel and Ethinylestradiol in Healthy Postmenopausal Women and Furosemide and Rosuvastatin in Healthy Subjects.
Clin Pharmacokinet
; 60(9): 1171-1185, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33782832
10.
Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent.
Pharmacol Res Perspect
; 9(1): e00690, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33340279
11.
Depletion of LAG-3+ T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781.
Clin Pharmacol Ther
; 109(5): 1293-1303, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33113155
12.
The Pharmacokinetics and Relative Bioavailability of Mepolizumab 100 mg Liquid Formulation Administered Subcutaneously to Healthy Participants: A Randomized Trial.
Clin Pharmacol Drug Dev
; 9(3): 375-385, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31317668
13.
Phase 1 Pharmacokinetic Study of AZD5718 in Healthy Volunteers: Effects of Coadministration With Rosuvastatin, Formulation and Food on Oral Bioavailability.
Clin Pharmacol Drug Dev
; 9(3): 411-421, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31793171
14.
The Association for Human Pharmacology in the Pharmaceutical Industry London Meeting October 2019: Impending Change, Innovation, and Future Challenges.
Front Pharmacol
; 11: 580560, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33364955
15.
Safety, Tolerability, and Pharmacokinetics of the Mineralocorticoid Receptor Modulator AZD9977 in Healthy Men: A Phase I Multiple Ascending Dose Study.
Clin Transl Sci
; 13(2): 275-283, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31584739
16.
The Association for Human Pharmacology in the Pharmaceutical Industry London Meeting 2018: Brexit and Other Challenges in Early Phase Drug Development.
Front Pharmacol
; 9: 1301, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30510508
17.
Pharmacokinetic Evaluation of Once-Weekly and Once-Monthly Buprenorphine Subcutaneous Injection Depots (CAM2038) Versus Intravenous and Sublingual Buprenorphine in Healthy Volunteers Under Naltrexone Blockade: An Open-Label Phase 1 Study.
Adv Ther
; 34(2): 560-575, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28070862
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